Low-calorie diets: It is harmful to reduce your daily calorie intake lower than 1400 calories per day, because your body adjusts to a semi-starvation state and looks for alternative sources of energy. In addition to burning fat, your body will eventually burn muscle tissue. Because your heart is a muscle, prolonged starvation will weaken it and interfere with its normal rhythms. Low-calorie diets don't meet the body's nutrition needs, and without nutrients your body cannot function normally.
It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients.[22] It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction.[3]
"When going out for fast food, I used to get the large-size value meal. Now, I satisfy a craving by ordering just one item: a small order of fries or a six-piece box of chicken nuggets. So far, I've shaved off 16 pounds in seven weeks, and I'm on track to being thinner than my high school self for my 10-year reunion later this year." —Miranda Jarrell, Birmingham, AL
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