The brain is composed of a network of neurons that transmit signals by propagating nerve impulses. The propagation of this impulse from one neuron to another is typically controlled by neurotransmitters, though there are also electrical pathways between some neurons. Neurotransmitters can inhibit impulse firing (primarily done by γ-aminobutyric acid, or GABA) or they can excite the neuron into firing (primarily done by glutamate). A neuron that releases inhibitory neurotransmitters from its terminals is called an inhibitory neuron, while one that releases excitatory neurotransmitters is an excitatory neuron. When the normal balance between inhibition and excitation is significantly disrupted in all or part of the brain, a seizure can occur. The GABA system is an important target for anticonvulsant drugs, since seizures may be discouraged by increasing GABA synthesis, decreasing its breakdown, or enhancing its effect on neurons.
Obesity among children and adults dramatically increases the risk of chronic illnesses such as heart disease and type 2 diabetes. What are the contributing factors that lead to being overweight? In this seminar, Harvard Medical School doctors and researchers will address the stigma that surrounds obesity and discuss concrete methods, including changes to sleep and diet, that could help scale back this growing problem. Each spring, Harvard Medical School's Office of Communications and External Relations organizes a series of four free "mini-med school" classes for the general public in the heart of Boston's Longwood Medical Area. At the end of the seminar series, participants who attend three out of the four sessions receive a certificate of completion. Topics are selected for their appeal to a lay audience and have included the human genome, nutrition, sleep dynamics and health care access. Faculty from Harvard Medical School and its affiliate hospitals volunteer their time to present these lectures to the community. More »
I know it's cliché, but let me get specific: When I arrive at a party, I don’t go immediately to the food. I first think about how many hours I plan on being there and try to pace myself accordingly. If I know it’s a three-hour buffet dinner, I may not start eating until an hour into being there. I’ll focus on drinking lots of water first and talk to people, so I don’t stuff my face too early and overdo it.
Get the idea? You need to include lots of fruit and vegetables in your diet. This really helps you feel full, without packing in the calories. As you can see in these two options, you can still add a few extra snacks or calories if you still feel hungry at meal or snack-time. You can always check your food’s calories by using one of the various calorie calculators available online such as the one offered by WebMD. Also notice that the only included drink is coffee. Avoid sugary drinks, alcohol and soda, as these will add a lot of calories. Instead, drink plenty of water or herbal tea. If you find plain water too boring to drink- you can add a bit of lemon or try one of the many cucumber water recipes available in this post.
"When going out for fast food, I used to get the large-size value meal. Now, I satisfy a craving by ordering just one item: a small order of fries or a six-piece box of chicken nuggets. So far, I've shaved off 16 pounds in seven weeks, and I'm on track to being thinner than my high school self for my 10-year reunion later this year." —Miranda Jarrell, Birmingham, AL