The nerve impulse is characterised by a great influx of sodium ions through channels in the neuron's cell membrane followed by an efflux of potassium ions through other channels. The neuron is unable to fire again for a short time (known as the refractory period), which is mediated by another potassium channel. The flow through these ion channels is governed by a "gate" which is opened by either a voltage change or a chemical messenger known as a ligand (such as a neurotransmitter). These channels are another target for anticonvulsant drugs.[7]
For long-term success, it is recommended to avoid short fad diets and focus on a gradual lifestyle change. Start eliminating processed foods, and begin eating a mostly organic, plant-based whole food diet with plenty of vegetables, fruits, whole grains, seeds, nuts, beans, and legumes. Exercise at least 20 – 30 minutes a day. Get enough sleep, reduce stress, and practice a positive mindset.
Infants and patients fed via a gastrostomy tube can also be given a ketogenic diet. Parents make up a prescribed powdered formula, such as KetoCal, into a liquid feed.[18] Gastrostomy feeding avoids any issues with palatability, and bottle-fed infants readily accept the ketogenic formula.[30] Some studies have found this liquid feed to be more efficacious and associated with lower total cholesterol than a solid ketogenic diet.[3] KetoCal is a nutritionally complete food containing milk protein and is supplemented with amino acids, fat, carbohydrate, vitamins, minerals and trace elements. It is used to administer the 4:1 ratio classic ketogenic diet in children over one year. The formula is available in both 3:1 and 4:1 ratios, either unflavoured or in an artificially sweetened vanilla flavour and is suitable for tube or oral feeding.[50] Other formula products include KetoVolve[51] and Ketonia.[52] Alternatively, a liquid ketogenic diet may be produced by combining Ross Carbohydrate Free soy formula with Microlipid and Polycose.[52]

The main advantage of the low-carb diet is that it causes you to want to eat less. Even without counting calories most overweight people eat far fewer calories on low carb. Sugar and starch may increase your hunger, while avoiding them may decrease your appetite to an adequate level. If your body wants to have an appropriate number of calories you don’t need to bother counting them. Thus: Calories count, but you don’t need to count them.


Obesity among children and adults dramatically increases the risk of chronic illnesses such as heart disease and type 2 diabetes. What are the contributing factors that lead to being overweight? In this seminar, Harvard Medical School doctors and researchers will address the stigma that surrounds obesity and discuss concrete methods, including changes to sleep and diet, that could help scale back this growing problem. Each spring, Harvard Medical School's Office of Communications and External Relations organizes a series of four free "mini-med school" classes for the general public in the heart of Boston's Longwood Medical Area. At the end of the seminar series, participants who attend three out of the four sessions receive a certificate of completion. Topics are selected for their appeal to a lay audience and have included the human genome, nutrition, sleep dynamics and health care access. Faculty from Harvard Medical School and its affiliate hospitals volunteer their time to present these lectures to the community. More »

Did bikini season sneak up on you? Is your soon-to-be worn wedding dress still just a touch too tight? Did a last-minute invite for a beach getaway come your way? You're a lucky dog – and a panicked one too because you want to drop pounds, and fast. These 10 diets are likely to help you lose significant weight within a year, according to a panel of experts who reviewed 38 plans for the U.S. News Best Diets rankings. Just remember: Short-term weight loss is markedly different from long-term weight loss, which is more important for your health.
When you eat foods high in carbohydrates and fat, your body naturally produces glucose. Carbohydrates are the easiest thing for the body to process, and therefore it will use them first – resulting in the excess fats to be stored immediately. In turn, this causes weight gain and health problems that are associated with high fat, high carbohydrate diets (NOT keto).
Unintentional weight loss can occur because of an inadequately nutritious diet relative to a person's energy needs (generally called malnutrition). Disease processes, changes in metabolism, hormonal changes, medications or other treatments, disease- or treatment-related dietary changes, or reduced appetite associated with a disease or treatment can also cause unintentional weight loss.[26][27][28][32][33][34] Poor nutrient utilization can lead to weight loss, and can be caused by fistulae in the gastrointestinal tract, diarrhea, drug-nutrient interaction, enzyme depletion and muscle atrophy.[28]
If you're wondering about weight loss? Yes, you will lose some weight on the military diet if you're used to eating a couple thousand calories per day (just like any diet that restricts your calorie intake), according to Amidor. However, it's likely you'll go back to your old eating habits and gain the weight right back once you're off the diet, which can create a vicious cycle, she says.
The researchers agree that the diet itself isn’t inherently dangerous. But, cautions Weiss, “If you have any medical condition, if you take any medicine at all – there are lots of things that change how medicines work in our bodies, and nutrition is definitely one of them. If you’re making a real change in your nutrition, you really should talk to your doctor.”
Watching that extra junk around your trunk turn your body into a full-blown Buddha belly puts you at an increased risk for heart disease, diabetes, and early death. Luckily, losing the weight doesn’t have to take forever; with these 22 belly fat-fighting tips, you can shave two inches off your waistline in as little as two weeks. Think your age will stand in the way of your weight loss? The 20 Ways to Lose Your Belly When You’re Older will help folks of any age get on track to their best body ever.
1. The side plank exercise is the best way to reduce belly fat. There are only two points of contact with the floor which helps the core muscles to contract even harder. Lie on your side with your legs top of each other, rest on your lower forearm that is bent on the elbow. Force your upper body off the floor by using your forearm and place other hand on your hips. You should resemble a diagonal line from head to toe. After you lift your bodies just hold it for 30-60 seconds.
During the 1920s and 1930s, when the only anticonvulsant drugs were the sedative bromides (discovered 1857) and phenobarbital (1912), the ketogenic diet was widely used and studied. This changed in 1938 when H. Houston Merritt, Jr. and Tracy Putnam discovered phenytoin (Dilantin), and the focus of research shifted to discovering new drugs. With the introduction of sodium valproate in the 1970s, drugs were available to neurologists that were effective across a broad range of epileptic syndromes and seizure types. The use of the ketogenic diet, by this time restricted to difficult cases such as Lennox–Gastaut syndrome, declined further.[10]
The ketogenic diet is a mainstream dietary therapy that was developed to reproduce the success and remove the limitations of the non-mainstream use of fasting to treat epilepsy.[Note 2] Although popular in the 1920s and 30s, it was largely abandoned in favour of new anticonvulsant drugs.[1] Most individuals with epilepsy can successfully control their seizures with medication. However, 20–30% fail to achieve such control despite trying a number of different drugs.[9] For this group, and for children in particular, the diet has once again found a role in epilepsy management.[1][10]

Dinner on day 2 is also heavy on meat, this time in the form of hot dogs, which are a source of protein and fat. You’ll also get Vitamin B-6, Vitamin B-2, iron, calcium and sodium from the hot dogs. The broccoli, carrots and banana are where you’ll get lots more vitamins and minerals- including all the Vitamin C and A that you need for the day. In addition, they contain potassium, iron, calcium, fiber and Vitamin B-6. Don’t forget your ice cream!
If you don't eat meat — or any animal products, for that matter — or if you have a food allergy, you can replace anything on the meal plan with foods that have a similar calorie count and provide the same nutrients. For example, instead of eating half a cup of tuna, you can eat about 2/3 cup of tofu. Instead of eating an egg at breakfast, you can drink a cup of soy milk. On day two of the military diet, cottage cheese substitution ideas include 15-20 almonds. Almonds work to sub out the slice of cheddar cheese, too. And instead of peanut butter, you can spread almond butter or sunflower butter on your toast for breakfast of day one.

And like all crash-diets known to man, Alpert says the military diet is meant to make only a short-term impact instead of teaching positive eating habits that can be sustained for a long, healthy life. As a result, she says it's very likely participants will gain back any weight lost shortly after concluding the diet. (Really. You should stop restrictive dieting.)
This high-fat, adequate-protein, low-carb fad diet sends the body into a state of ketosis, in which the body uses stored fat for energy. Research published in Clinical Cardiology suggests the ketogenic, or “keto,” diet can be an effective weight loss method, but to be successful, you must follow the plan consistently with no cheat days — otherwise, you’re just eating a high-fat diet that may be high in unhealthy fats for no reason. (1) (A pro tip? If you're planning on doing the diet, consider perusing this complete keto food list and reading up on the healthiest fats for keto diet followers.)
For the first three days, the diet consists of three distinct meal plans. For the first day, breakfast consists of half a grapefruit, a slice of whole-wheat toast with 2 tablespoons of peanut butter, and a cup of caffeinated black tea or coffee. If you can't drink it black, it's recommended you sweeten it with a natural sugar substitute, like Stevia. For lunch, have half a cup of tuna (you can buy 3 oz or 5 oz cannes of cooked tuna, or prepare it yourself), one slice of whole-wheat toast, and a second cup of black coffee or tea. Dinner is the more filling meal, consisting of 3 oz of meat, one cup of green beans, half a banana, one small apple, and one cup of vanilla ice cream for dessert.
Is Keto Worth It? Know The Health Benefits And Risks Before Going On A Keto DietThe ketogenic diet helps to bring your body into a metabolic state which is known as the ketosis. Ketosis occurs when the body has run out of its glycogen (which is basically sugar) stores so it needs to find another source of fuel.  By: DoctorNDTV  Updated: Dec 8, 2018 10:12 IST 4-Min Read 25 SHARES The primary goal of the ketogenic diet is weight loss.
When you substitute foods, make sure you don’t use the same amount of the substitute as the original without checking caloric equivalence first. For example, if you want to substitute Greek yogurt for cottage cheese, you can actually eat a bit more of the yogurt than the prescribed amount of cottage cheese. Just 1 cup of 2% cottage cheese contains 194 calories, while 1 cup of 2% Greek yogurt contains 150 calories, meaning you can have additional 1/3 cup of the yogurt. Make use of a calorie calculator if you’re not sure about your allowances.   
When I go to big meals at family-style restaurants or people’s homes, I keep my appetizer or salad plate for the entrée course. I load up on a lot of food during both courses but using the slightly smaller plate helps. I've also learned to fill my plates with mostly veggies. I will still gladly take a spoonful of mac and cheese, but I'm careful not to take more than that because I know that if it’s on the plate, it will end up in my mouth.
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