It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients.[22] It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction.[3]
A computer program such as KetoCalculator may be used to help generate recipes.[46] The meals often have four components: heavy whipping cream, a protein-rich food (typically meat), a fruit or vegetable and a fat such as butter, vegetable oil or mayonnaise. Only low-carbohydrate fruits and vegetables are allowed, which excludes bananas, potatoes, peas and corn. Suitable fruits are divided into two groups based on the amount of carbohydrate they contain, and vegetables are similarly divided into two groups. Foods within each of these four groups may be freely substituted to allow for variation without needing to recalculate portion sizes. For example, cooked broccoli, Brussels sprouts, cauliflower and green beans are all equivalent. Fresh, canned or frozen foods are equivalent, but raw and cooked vegetables differ, and processed foods are an additional complication. Parents are required to be precise when measuring food quantities on an electronic scale accurate to 1 g. The child must eat the whole meal and cannot have extra portions; any snacks must be incorporated into the meal plan. A small amount of MCT oil may be used to help with constipation or to increase ketosis.[36]
Some antidepressant medications can cause weight gain, especially the older tricyclic antidepressants (TCAs) such as Tryptizol, Saroten, and Clomipramine; as well as newer drugs such as Remeron (Mirtazapine). Lithium (for manic-depressive disorder) often causes weight gain. The most common antidepressants known as SSRI’s (for example Citalopram and Sertraline) usually don’t impact weight significantly. More on depression
Our increasingly slothful lifestyles are partly to blame for skyrocketing obesity rates, so it’s no surprise that being more active is a simple fix for belly fat. In 2003, a first-of-its-kind study from Duke University showed that sedentary adults accumulated abdominal fat surprisingly quickly — and that sedentary women stacked on fat more visceral fat than sedentary men, even though they added less fat overall.

The benefits above are the most common ones. But there are others that are potentially even more surprising and – at least for some people – life changing. Did you know that a keto diet can help treat high blood pressure, may result in less acne, may help control migraine, might help with certain mental health issues and could have a few other potential benefits?

Some diet plans, such as the MIND diet and the DASH diet, are meant to focus on certain areas of health — and weight loss may be a bonus. Others are created with weight loss as a primary goal. “It is important to remember that we are all very unique individuals,” says Kyle. “We all have different states of health and different lifestyles, which could affect what diet plan is best for us. That means that you should not be considering what is working for your friends or family members — and instead should pay attention to what works for you individually.”

We weren't joking when we said gut flora was important—when it's out of whack, the way your body breaks down calories is also impacted and it's all to do with two kinds of fat cells: white and brown. The white ones cause obesity and insulin resistance when there are too many hanging around, and insulin resistance makes it super difficult to burn fat despite working out like a #boss. Brown fat cells, on the other hand, protect the body against excess weight, and the more you have, the more calories you can burn. So the goal is to have white fat cells turn into brown ones as often as possible. That happens when your gut flora is in check (with that balanced diet we talked about above), you exercise, and get enough sleep, as melatonin cues up the production of brown fat cells. 


If you want to know how to lose belly fat then listen up: cutting out carbs and forcing your body through endless HIIT workouts aren't the answer for shifting lbs from your midriff. In fact, there's no one formula to spot reduce a wobbly waist because several factors affect how to lose belly fat: mental well being, cortisol levels, hormones, nutrition, the intensity of your workouts all play a part.
For even more impressive effects on body composition: aim for exercise forms which elicit a positive hormonal response. This means lifting really heavy things (strength training), or interval training. Such exercise increases levels of the sex hormone testosterone (primarily in men) as well as growth hormone. Not only do greater levels of these hormones increase your muscle mass, but they also decrease your visceral fat (belly fat) in the long term.
That’s why many health experts are concerned about people on the keto diet, especially those who try it without the guidance of a doctor or nutritionist. Doctors say that high-fat diets like this one may raise cholesterol levels, and some studies suggest that they increase the risk of diabetes. Some have even called it a “cardiologist’s nightmare.”
We weren't joking when we said gut flora was important—when it's out of whack, the way your body breaks down calories is also impacted and it's all to do with two kinds of fat cells: white and brown. The white ones cause obesity and insulin resistance when there are too many hanging around, and insulin resistance makes it super difficult to burn fat despite working out like a #boss. Brown fat cells, on the other hand, protect the body against excess weight, and the more you have, the more calories you can burn. So the goal is to have white fat cells turn into brown ones as often as possible. That happens when your gut flora is in check (with that balanced diet we talked about above), you exercise, and get enough sleep, as melatonin cues up the production of brown fat cells. 
“A lot of people think the foundation of a paleo diet is high-fat meat, but I suggest that it’s vegetables,” says Hultin. The concept is to eat only foods — including meat, fish, poultry, eggs, fruits, and vegetables — that would have been available to our Paleolithic ancestors. This means grains, dairy, legumes, added sugar, and salt are all no-no’s.
When I go to big meals at family-style restaurants or people’s homes, I keep my appetizer or salad plate for the entrée course. I load up on a lot of food during both courses but using the slightly smaller plate helps. I've also learned to fill my plates with mostly veggies. I will still gladly take a spoonful of mac and cheese, but I'm careful not to take more than that because I know that if it’s on the plate, it will end up in my mouth.
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