^ Freeman JM, Vining EP, Pillas DJ, Pyzik PL, Casey JC, Kelly LM. The efficacy of the ketogenic diet—1998: a prospective evaluation of intervention in 150 children. Pediatrics. 1998 Dec;102(6):1358–63. doi:10.1542/peds.102.6.1358. PMID 9832569. https://web.archive.org/web/20040629224858/http://www.hopkinsmedicine.org/press/1998/DECEMBER/981207.HTM Lay summary]—JHMI Office of Communications and Public Affairs. Updated 7 December 1998. Cited 6 March 2008.
Slow down, we're not saying you have diabetes. But insulin resistance is "the beginning of your body not dealing well with sugar and carbohydrates," says Melina Jampolis, M.D., author of The Doctor On Demand Diet..  Basically, when you have insulin resistance, it means the body's cells have noticed an increase in sugar in the blood and ratchet up the amount of insulin to transport it to cells that process it for energy. A vicious cycle gets started, you create more insulin—too much of it, in fact—and your cells become resistant to it, leading to more free-floating sugar in your blood stream that eventually gets converted to fat and is usually stored in your belly. Unless you reverse the insulin resistance, your body will keep going round and round, and diabetes could develop. The key, says Jampolis, is to lose fat and build muscle. "Exercise, especially strength training, can improve your body's response to insulin even if you don't lose an ounce," Jampolis explains. Try lifting weights two to three times a week—these moves are great fat-blasters. 
Those trans fats on your menu are hiding out in plain sight and sabotaging your lean belly plans every time you eat them. If a food product says it contains partially hydrogenated oils, you’re eating trans fat, which can increase your risk of heart disease, high cholesterol, and obesity with every bite. In fact, research conducted at Wake Forest University reveals that monkeys whose diets contained eight percent trans fat upped their body fat by 7.2 percent over a six-year study, while those who ate monounsaturated fat gained just a fraction of that amount. Instead of letting harmful trans fat take up space on your menu, fill up with the 20 Healthy Fats to Make You Thin.

"One of the hardest parts of losing weight is maintaining the lifestyle changes you’ve made. It’s difficult to stay motivated all the time, especially if you’ve slipped up along the way. But don’t let this affect your end goal. If you’re feeling particularly unmotivated, ask a friend to join you for your workout and then afterwards cook something healthy for dinner together."
Obviously, it’s still possible to lose weight on any diet – just eat fewer calories than you burn, right? The problem with this simplistic advice is that it ignores the elephant in the room: Hunger. Most people don’t like to “just eat less”, i.e. being hungry forever. That’s dieting for masochists. Sooner or later, a normal person will give up and eat, hence the prevalence of “yo-yo dieting”.
Some antidepressant medications can cause weight gain, especially the older tricyclic antidepressants (TCAs) such as Tryptizol, Saroten, and Clomipramine; as well as newer drugs such as Remeron (Mirtazapine). Lithium (for manic-depressive disorder) often causes weight gain. The most common antidepressants known as SSRI’s (for example Citalopram and Sertraline) usually don’t impact weight significantly. More on depression
But don’t lose hope just yet. You can still incorporate strategies that help you lose total body fat, which will benefit your belly. At the end of the day, nothing sheds belly fat like diet, exercise, and everyday changes to your lifestyle. The slimmer stomach of your dreams is always within reach, but it takes time and dedication. Commit to these habits, and you’ll start dropping pounds before you know it.
So what happens when you can’t exercise? There are many people with health and physical difficulties who can’t exercise in the traditional way. For those people, I assure you that you can still lose weight. Like I said above, weight loss is 70% what you eat and 30% exercise, so if you can’t exercise you have to be spot on with your diet plan to lose weight.
I’ve never been one to focus too much on “mindful eating” because the idea of meditating on a grape is not my style. But I learned it does take more than that just focusing on what's on my plate. And yes, that means to eat more consciously. Here, I'm sharing the weight-loss tips and rules that work for me (and a glimpse at what you'd find on my 2B Mindset program).
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